Late-onset liver metastases from melanoma: two case reports and review of the literature


Auteurs: 

Y Abdourabbih, I Chaouche, H Ouazzani, A Akammar, N El Bouardi, H Meryem, B Alami, M Boubbou, M Maaroufi, MY Alaoui Lamrani


Date de publication : 

30-Mar-2026

Résumé

Malignant melanoma is the most aggressive form of skin cancer, due to its high metastatic potential and the possibility of late recurrences, sometimes occurring many years after treatment of the primary tumor. These late metastases are often initially asymptomatic and may present with non specific clinical features, posing a significant diagnostic challenge. Among visceral sites, hepatic involvement is particularly important because of its severity and prognostic impact. We report two cases of female patients presenting with right upper quadrant pain, in whom imaging revealed multiple liver lesions, and in whom liver biopsy confirmed metastatic melanoma consistent with their initial cutaneous and choroidal tumors. These cases illustrate the phenomenon of late onset liver metastases, underscore the role of MRI in detecting melanin containing lesions, and highlight important diagnostic pitfalls and clinical implications for long term follow up.

Mot-clés :

Malignant Melanoma, Late Metastases, Liver Metastases, Mri

Autres détails
Volume 1 (2026)
Numéro 1
DOI 10.70065/2611.jaccrImaging.002L013003
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